Description

This book gathers scientific expertise and traditional knowledge to promote the discovery and development of new formulations and drugs based on active ingredients and to provide guidance on taking these to clinical trials.

Active botanical ingredients are a prime requirement for herbal formulations and discovering a drug is all about integration of science disciplines. In recent decades there has been a growing interest in treating wounds and diseases using traditional remedies based on local herbs, combined with chemical advances. Although this has led to the development of new bioactive ingredients from plants, there has been little success in terms of clinical trials and post-marketing studies to comply with FDA guidelines. Plants have been used as a source of medicine throughout history and continue to serve as the basis for many pharmaceuticals used today. However, despite the modern pharmaceutical industry being founded on botanical medicine, synthetic approaches to drug discovery have now become standard. Science-driven translational discovery and botanical development has created a new reality, leading to enormous changes in strategies, technologies and the disciplines involved, which have been embraced by the pharmaceutical and biotech industries.

This book gathers scientific expertise and traditional knowledge to promote the discovery and development of new formulations and drugs based on active ingredients and to provide guidance on taking these to clinical trials. It discusses major topics, such as how the phytochemical composition of many plants has changed over time due to factors like cultivation, which can have both positive and negative effects on the levels of bioactive compounds. It also explores the importance of plants as a valuable source of therapeutic compounds as a result of their vast biosynthetic capacity, and classifies them according to their intended use, safety and regulatory status. Further, the book offers insights into the regulatory aspects of botanical products, which is an important issue when considering standardization and quality assessment, and also examines the commercial aspects of plant-derived medications and their proven role in the treatment of chronic diseases such as heart disease, high blood pressure, pain, asthma, and other associated conditions. Given its scope, this book is a valuable tool for botanists, natural product chemists, pharmacologists and microbiologists involved in the study of phytochemicals for drug discovery.

LangueenVersionBrochéDate de sortie initiale07 octobre 2021Nombre de pages468IllustrationsAvec illustrations

Personnes impliquées

Auteur principal

Bikarma Singh

Rédacteur en chef

Bikarma Singh

Editeur principal

Springer Verlag, Singapore

Informations sur le fabricant

Nom du fabricantSpringer Nature Customer Service Center GmbHAdresse du fabricant– 69115 – – DEAdresse électronique du fabricant[email protected]Informations sur le fabricantLes informations du fabricant ne sont actuellement pas disponibles

Autres spécifications

Hauteur de l’emballage235 mmLargeur d’emballage155 mmLargeur du produit155 mmLivre d‘étudeNonLongueur d’emballage235 mmLongueur du produit235 mmPoids de l’emballage885 gÉdition1st ed. 2020

EAN

EAN9789811559198

Sécurité des produits

Opérateur économique responsable dans l’UE

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Catégories

Science et nature

Médecine et Soins infirmiers

Médecine spécialisée

Chimie

Pathologie

Microbiologie médicale et Virologie

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Anglais

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Paperback